Sub-Saharan Africa

Neonatal guideline adherence in sub-Saharan Africa is often below the World Health Organization recommended standard of 80%. Malaria incidence varies substantially across sub-Saharan Africa, showing uneven effects of interventions. AKI patients in sub-Saharan Africa differ meaningfully from those in high-income countries. Sub-Saharan African AKI patients tend to be younger and have lower rates of diabetes and hypertension than patients in high-income countries. RRI thresholds developed in high-income populations may not directly translate to sub-Saharan African contexts. Country or region will be used in subgroup analyses and meta-regression to explore diagnostic accuracy variation. Reported adherence to practices including thermal care, early breastfeeding, vitamin K administration, and cord care ranges from 23% to 66%. Birth asphyxia and sepsis protocols show poor adherence in the region. SSA-specific cultural, infrastructural, and socioeconomic conditions make regional evaluation of mHealth efficacy a research priority. The predictive performance of RRI for AKI in sub-Saharan Africa may differ substantially from other regions. The review aims to identify culturally appropriate…