Subcellular Components
The model considers but disfavors the idea that asymmetry mainly reflects the cost of making beneficial components divide symmetrically. The compounds responsible for asymmetry in unstressed E. coli remain unidentified. Protein aggregates…
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The model considers but disfavors the idea that asymmetry mainly reflects the cost of making beneficial components divide symmetrically. The compounds responsible for asymmetry in unstressed E. coli remain unidentified. Protein aggregates partition asymmetrically in E. coli and reduce fitness under stress. Partitioning damaging compounds better matches the observed existence of two similar equilibria under diminishing returns from asymmetric division.