Substances

The source does not claim to know whether cannabis effects reliably differ by route of administration. The article says a study of 1,000 marijuana users found lower activity in every brain area. Dependence with withdrawal is proposed as a practical warning sign that a substance may not support brain health. Alcohol, marijuana, and nicotine are described as substances that may impair frontal lobes and trade short-term happiness for long-term costs. Cannabis is described as potentially creating short-term happiness while being problematic in many clinical cases.