Sugar-Driven Dysbiosis

The article rejects a simple model in which sugar causes type 2 diabetes only by directly exhausting the pancreas. The article presents type 2 diabetes as partly arising from a cascade linking diet, microbial shifts, leaky gut, LPS, inflam…

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The article rejects a simple model in which sugar causes type 2 diabetes only by directly exhausting the pancreas. The article presents type 2 diabetes as partly arising from a cascade linking diet, microbial shifts, leaky gut, LPS, inflammation, and insulin signaling disruption. Sugar can favor yeast and unfavorable bacteria. Yeast overgrowth may reinforce sugar cravings through mycotoxins that affect the brain. Excess sugar and processed foods are described as inputs that shift the microbiome.