Syncope

The negative association between syncope history and long-term physical activity was especially pronounced in men and in participants with normal BMI. Pre-TAVR syncope history was present in 27.37% of the study cohort. Syncope is common in severe aortic stenosis and involves abrupt transient loss of consciousness, inability to maintain posture, falls, and rapid spontaneous recovery. Syncope was clinically defined as abrupt, transient, complete loss of consciousness with inability to maintain postural tone and rapid spontaneous recovery, attributed to cerebral hypoperfusion. Men may be more vulnerable to reducing activity after syncope because of fear and caution, despite typically engaging in higher baseline levels of physical activity. After multivariate adjustment, prior syncope history was independently associated with lower odds of being physically active at least two years after TAVR, with an adjusted odds ratio of 0.287.