Systemic Inflammation

The purpose of the functional medicine evaluation is to improve treatment success and avoid returning the patient to the same inflammatory environment. Twice-daily body lotion use reportedly decreased inflammatory cytokines, specifically IL-8, after three months. An anti-inflammatory diet is recommended for at least two weeks before and after treatment. The clinical significance and magnitude of systemic inflammation reduction from treating skin inflammation require more evidence. Excess body fat is a state of chronic systemic inflammation, not primarily a cosmetic issue. The proposed systemic effect of OS-01 body treatment is indirect through healthier, less inflamed skin rather than direct peptide delivery into blood. The source attributes chronic pain non-resolution partly to systemic inflammation and broader health factors. Inflamed or damaged skin is presented as both a marker and contributor to systemic inflammation. Expanded adipose tissue secretes pro-inflammatory cytokines that damage blood vessels and compromise organ function over time. Neuroinflammation driven by caloric overload and high sugar intake is directly associated with elevated risk of depression and anxiety.…