Systemic Lupus Erythematosus
A lupus nephritis patient requiring haemodialysis recovered renal function after CAR T infusion. CAR T-mediated depletion in SLE produces transcriptional effects that differ from conventional pharmacotherapy. SLE is the most developed auto…
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A lupus nephritis patient requiring haemodialysis recovered renal function after CAR T infusion. CAR T-mediated depletion in SLE produces transcriptional effects that differ from conventional pharmacotherapy. SLE is the most developed autoimmune indication for CAR T therapy in the article. SLE-specific CAR T guidance has been developed by a multi-partner, multi-disciplinary working group.