Therapeutic Timing

The therapeutic window lasted one to three days. Brain connectivity patterns began reforming by days three to four. By the time severe bilateral infiltrates and profound hypoxemia appear, the virus may already be cleared. The point of maximum antiviral leverage is early in infection, before the cascade of vascular and inflammatory injury becomes self-sustaining. A therapeutic window emerged after ketamine administration. Antiviral medications like Remdesivir offer limited benefit after the virus has already been cleared by the immune system.