Three-Body-Systems Model

The model maps neuroendocrine, GI, and detoxification systems to adrenal or hormone panels, stool analysis, and organic acids or metabolomics testing. The proposed damage sequence is neuroendocrine dysfunction first, then GI dysfunction, then toxic burden. A stressed neuroendocrine system is described as weakening the gut lining and disrupting the microbiome. The article presents illness development as a sequence beginning with neuroendocrine dysregulation. Impaired digestion and a compromised gut barrier are said to contribute to toxin accumulation and systemic toxicity over time.