Time in Therapeutic Range
Chinese patients achieve a mean TTR of approximately 55%, substantially below the 60–77% observed in developed nations. The usual care arm's low TTR of 55.1% combined with a 12-month follow-up and 556 participants gave this trial adequate…
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Chinese patients achieve a mean TTR of approximately 55%, substantially below the 60–77% observed in developed nations. The usual care arm's low TTR of 55.1% combined with a 12-month follow-up and 556 participants gave this trial adequate statistical power to detect adverse event differences. TTR is calculated using Rosendaal's linear interpolation method applied to all INR values collected. Time in therapeutic range (TTR) is the standard metric of anticoagulation quality. Higher testing frequency in PST directly drove improved TTR and reduced extreme INR values in both the subtherapeutic and supratherapeutic directions.