Tissue-Specific Expression
The paper interprets reproductive and nervous-system tissues as major sites of long-life motif-associated ncRNA activity. Both humans and mice showed GGTGCG-rich ncRNA genes expressed in cerebral cortex-related tissues, suggesting a shared…
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The paper interprets reproductive and nervous-system tissues as major sites of long-life motif-associated ncRNA activity. Both humans and mice showed GGTGCG-rich ncRNA genes expressed in cerebral cortex-related tissues, suggesting a shared nervous-system component. The study examined tissue expression of ncRNA genes containing many GGTGCG motifs in humans and mice. CASC15 was most highly expressed in endometrium, ovary, and cerebral cortex. The top three human ncRNA genes containing GGTGCG were CASC15, LINC02934, and ENSG00000286481. In mice, Snhg14 and 9530036O11Rik were the only ncRNA genes with more than 20 GGTGCG motifs.