Treatment Toxicities

Breast cancer-related lymphoedema is defined using arm circumference or volume differences confirmed clinically. Cardiotoxicity is defined by reduced left ventricular ejection fraction or new abnormal global longitudinal strain. Reported toxicities include pain, lymphoedema, fatigue, anxiety, depression, sleep disturbance, cognitive change, and cardiotoxicity. Cancer-related fatigue can persist for years after treatment. Breast cancer treatments can cause acute and chronic adverse effects affecting recovery and everyday function.