Trichothecenes
Type A trichothecenes include T-2 and HT-2 toxins and are described as more toxic than Type B. Trichothecenes block protein synthesis, cause oxidative damage, interfere with DNA expression, and lead to cell death. Acute trichothecene expos…
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Type A trichothecenes include T-2 and HT-2 toxins and are described as more toxic than Type B. Trichothecenes block protein synthesis, cause oxidative damage, interfere with DNA expression, and lead to cell death. Acute trichothecene exposure can cause lethargy, ataxia, abdominal pain, nausea, vomiting, appetite loss, and immune or neuroendocrine changes. Trichothecenes are produced by Fusarium, Myrothecium, Stachybotrys, and Trichothecium fungi. Trichothecenes can enter the body through skin contact, inhalation, or oral exposure.