Tuberculosis Treatment Monitoring
The optimal LAM-change cut-off is selected using a combination of the Youden Index, a clinically acceptable false-negative rate, and alignment with WHO TPP targets. Treatment failure leads not only to poor patient outcomes but also to the…
1 sources - 5 claims
The optimal LAM-change cut-off is selected using a combination of the Youden Index, a clinically acceptable false-negative rate, and alignment with WHO TPP targets. Treatment failure leads not only to poor patient outcomes but also to the emergence and spread of drug-resistant TB. TB treatment failure is driven by long therapy duration and adherence difficulties. WHO recommends sputum culture and AFB smear microscopy to monitor treatment response in pulmonary TB.