Tumour Risk
P/LP variant carriers had substantially higher overall and malignant tumour incidence than children without P/LP or VUS-LP variants. P/LP carriers had poorer tumour-free probability and higher cumulative incidence than other patients. Cumu…
1 sources - 5 claims
P/LP variant carriers had substantially higher overall and malignant tumour incidence than children without P/LP or VUS-LP variants. P/LP carriers had poorer tumour-free probability and higher cumulative incidence than other patients. Cumulative tumour incidence increased notably after age 5 among P/LP and VUS-LP carriers. VUS-LP carriers had higher overall tumour incidence than children without P/LP or VUS-LP variants. For malignant tumours, VUS-LP carriers did not show a higher incidence rate than the no-variant group in this study.