Ulcer Medications

The triple therapy is administered orally for up to 90 days or until radiographic haematoma resolution. Goreisan is given at 7.5 g/day, carbazochrome sodium sulfonate hydrate at 90 mg/day, and tranexamic acid at 750 mg/day. Vitamin D achie…

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The triple therapy is administered orally for up to 90 days or until radiographic haematoma resolution. Goreisan is given at 7.5 g/day, carbazochrome sodium sulfonate hydrate at 90 mg/day, and tranexamic acid at 750 mg/day. Vitamin D achieved a 77.2% eradication rate of H. pylori, directly addressing the underlying cause of many ulcers. A previous retrospective study by the investigators suggested the triple-drug combination may reduce postoperative recurrence. A major cause of ulcers is the microbe Helicobacter pylori. The intervention combines Goreisan, carbazochrome sodium sulfonate hydrate, and tranexamic acid. Ulcer medications deplete vitamin D, removing the body's natural defense against the pathogen driving ulcers. All three drugs are off-label for preventing CSDH recurrence. Confirmed H. pylori infection is treated with combination therapy using antibiotics, PPIs, and sometimes bismuth. Eradication of H. pylori after treatment is confirmed using the urea breath test or stool antigen test. First-line regimens include triple therapy, bismuth quadruple therapy, and concomitant therapy protocols.