Urea Breath Test
The urea breath test is the most reliable non-invasive diagnostic method for H. pylori. The urea breath test achieves 95% sensitivity and specificity. H. pylori metabolizes ingested urea into measurable CO2, which is detected in the breath…
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The urea breath test is the most reliable non-invasive diagnostic method for H. pylori. The urea breath test achieves 95% sensitivity and specificity. H. pylori metabolizes ingested urea into measurable CO2, which is detected in the breath sample after 15 minutes. Interfering substances must be discontinued 2 to 4 weeks before urea breath testing. PPIs, bismuth compounds, antibiotics, and herbal antibiotics can compromise the accuracy of the urea breath test.