Value of Information
Collecting costs and HRQoL data greatly increased the expected value of sample information per patient. A follow-on RCT to reach the original ALABAMA target sample was estimated to cost £2.37 million and take 46 months. The optimal sample…
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Collecting costs and HRQoL data greatly increased the expected value of sample information per patient. A follow-on RCT to reach the original ALABAMA target sample was estimated to cost £2.37 million and take 46 months. The optimal sample size for maximum net return was estimated at 840 participants. Health-related quality-of-life outcomes were the highest-value research priority in the information analysis. The article estimates the ten-year cost of current suboptimal management at £19.6 million.