Volumetric MRI

Regional atrophy patterns differ between FTD subtypes such as bvFTD and PPA. Frontal and temporal lobe atrophy is an established sign of FTLD but has limited value for differentiating specific syndromes or pathologies on its own. MRI analy…

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Regional atrophy patterns differ between FTD subtypes such as bvFTD and PPA. Frontal and temporal lobe atrophy is an established sign of FTLD but has limited value for differentiating specific syndromes or pathologies on its own. MRI analysis approaches include visual review, ROI volumetry, VBM, and SPM. MRI volumetry is widely used in FTD and provides information about atrophy patterns that can distinguish FTD from other neurodegenerative diseases.