Weight-loss resistance

The article rejects a purely calorie-centered explanation for difficult weight loss in the case discussed. The article defines weight-loss resistance as failure to lose weight despite substantial diet and exercise effort. Repeated failure to lose weight is framed as a possible biological signal rather than poor effort. Starvation-style dieting is presented as unsustainable and potentially damaging even if it produces temporary weight loss. The article suggests that unexplained weight-loss resistance with chemical sensitivity, brain fog, and mold history warrants broader evaluation beyond diet and exercise habits.