WWARN

WWARN-hosted data have informed WHO malaria treatment guidelines for paediatric populations. A 2013 WWARN IPD-MA on dihydroartemisinin-piperaquine dosing contributed to WHO guideline revisions beginning in 2015 for children with malaria. WWARN supports fair attribution to LMIC data contributors as part of sustaining data reuse. A WWARN IPD-MA found lower efficacy and lower post-treatment prophylaxis effects of artemisinin-based combination therapies in acutely malnourished children under 5. Since 2009, WWARN has enabled IPD meta-analyses on safety, tolerability, and efficacy of several antimalarial drugs. WWARN is a malaria-focused research platform hosted within the Infectious Diseases Data Observatory at the University of Oxford.