Youth Depression RCTs
Psychological interventions were the most common intervention type among included studies. The evidence base was limited because it consisted of only two trials and 305 participants. The review included two RCTs, DREAMseq and SECOMBIT, wit…
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Psychological interventions were the most common intervention type among included studies. The evidence base was limited because it consisted of only two trials and 305 participants. The review included two RCTs, DREAMseq and SECOMBIT, with 305 total participants. Both included trials used intention-to-treat analyses and allowed crossover after disease progression. Most included trials were published between 2015 and 2025. Both trials were open-label, creating high risk of performance and detection bias.