Zearalenone
CYP450-mediated metabolism converts zearalenone into alpha and beta forms, with the alpha form being more toxic. Enterohepatic reabsorption prolongs zearalenone residence time and increases total toxic exposure. Zearalenone is produced exc…
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CYP450-mediated metabolism converts zearalenone into alpha and beta forms, with the alpha form being more toxic. Enterohepatic reabsorption prolongs zearalenone residence time and increases total toxic exposure. Zearalenone is produced exclusively by Fusarium species. Zearalenone is a non-steroidal estrogenic mycotoxin found in grains, soybeans, milk, and beer. Cholestyramine is uniquely indicated for zearalenone because it binds bile acids and interrupts recirculation.