Zinc Pyrithione
Zinc pyrithione shampoo normalized scalp histamine levels in dandruff patients — which were more than twice normal — back to levels seen in unaffected individuals. Zinc pyrithione acts against Malassezia through four simultaneous mechanism…
1 sources - 3 claims
Zinc pyrithione shampoo normalized scalp histamine levels in dandruff patients — which were more than twice normal — back to levels seen in unaffected individuals. Zinc pyrithione acts against Malassezia through four simultaneous mechanisms: inducing iron starvation, elevating intracellular zinc, disrupting mitochondrial function, and inhibiting lipase secretion. Zinc pyrithione inhibits Malassezia's lipase secretion, preventing the yeast from digesting sebum and effectively cutting off its food supply.